Toshiki Saito, MD, PhD



Clinical Research Center
Director, Department of Regenerative Medicine
Chief, Laboratory of Cell Therapy
Chief, Laboratory of Infomation System Research
Deputy Director, Department of Clinical Research Management
Chief, Division of Clinical Research Promotion
Chief, Division of Public Relations and Counseling



Tumor immunology
Transplantation biology
Humanized mice


Area of Research

Thymic progenitor cells
Humanized mice


Contact Information

Toshiki Saito, MD, PhD
National Hospital Organization Nagoya Medical Center
4-1-1 Sannomaru, Naka-ku, Nagoya
Aichi 460-0001, Japan
Office phone: +81-52-951-1111
Fax: +81-52-951-9075

Preferred contact method: e-mail



Dr. Saito’s current research interests focus on establishing a humanized mouse model that precisely reflects patient’s tumor and immune status including cellular immunology. Current projects include 1) transplantation of both hematopoietic stem cells and tumor into immunodeficient mice to mimick patient’s tumor and immune status. 2) Analysis on thymus development which is essential to develop cellular immunology.


Recent Award

MMRF 2007 Research Fellow Award



Toshiki Saito received his medical degree in 1994 and a PhD degree in 2003 from University of Tokyo, in Japan, and is a board certified Hematologist and major in hematopoietic stem cell transplantation. After residency training at University of Tokyo Hospital, Showa General Hospital and Kanbara General Hospital, he completed research fellowship at Transplantation Biology Research Center, Massachusetts General Hospital/Harvard Medical School under the supervision of Dr. Megan Sykes. In 2009, he took a position as a Assistant Professor of Hematology and Oncology at University of Tokyo. In 2010, he joined the staff of Nagoya Medical Center as a chief of the laboratory of Cell Therapy at Clinical Research Center.


Selected Publications

  1. Fujisaki J, et al. Nature. 2011;474:216-9
  2. Kumagai K, et al. Biol Reprod. 2011;84:682-8
  3. Saito TI, et al. J Immunol 2010;185:2099-105
  4. Saito TI, et al. Exp Hematol 2010;38:333-9
  5. Saito TI, et al. Exp Hematol 2006;34:1270-6
  6. Saito T, et al. Immunity 2003;18:675-85

Complete list of all publications.






Masahiro Sekimizu, MD